![]() Commercial licenses are also available.ġ3C metabolic flux analysis ( 13C MFA) has emerged over the past 20 years as an important approach to assess in vivo metabolic phenotypes ( Sauer, 2006 Wiechert, 2001). The generation of balance equations and their computational solution is completely automated and can be performed on networks of arbitrary complexity.Īvailability and implementation: MATLAB p-code files are freely available for non-commercial use and can be downloaded at. The software provides a framework for comprehensive analysis of metabolic networks using mass balances and elementary metabolite unit balances. Isotopomer network compartmental analysis (INCA) is the first publicly available software package that can perform both steady-state metabolic flux analysis and isotopically non-stationary metabolic flux analysis. ![]() The scope of these studies has gradually expanded to include both isotopically steady-state and transient labeling experiments, the latter of which are uniquely applicable to photosynthetic organisms and slow-to-label mammalian cell cultures. ![]() Summary: 13C flux analysis studies have become an essential component of metabolic engineering research. ![]()
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